Changes in the essential oil content and composition of <i>Salvia limbata</i> C.A. Mey at different growth stages and altitudes

Salvia limbata is of great importance to the pharmaceutical industry owing its various biological effects. Therefore, it important investigate main factors that affect essential oil composition. Although some investigations have been performed with regard phytochemistry S. limbata, this study investigates, for first time, effect growth stage and altitude on content chemical composition extracted from limbata. For purpose, was 45 air-dried samples by hydrodistillation analyzed GC–MS GC–flame methods. The highest obtained aerial parts in vegetative at an 1500 m (0.86% v/w). Our findings show optimal harvest time extract while monoterpenes (including ?-pinene ?-pinene) could be same phenological 2000 m. By contrast, sesquiterpenes increased values ripening 2500 results help find conditions obtain oil, but additional studies are warranted.